Triangular fuzzy number for similarity measurement of Y chromosome DNA profile

Meira Parma Dewi, Aniati Murni Arymurthy, Suryana Setiawan, Nurtami Soedarsono

Abstract


This study measures the similarity of the short tandem repeat (STR) profile of human DNA. The similarity measurement had been done to the STR value of the allele loci in DNA profile between the query’s DNA to the reference’s DNA profile. The measurements were conducted on 27 DNA profile loci including the Y chromosome loci (YSTR). The YSTR loci were used as the main comparison of similarity measurements to determine the biological kinship relationship between the query DNA profile and the alleged male biological family. To measure the similarity of two STR values that have shifted due to several factors in the DNA source extraction process, a fuzzy similarity measure was used. The STR values of the DNA profile loci are described as triangular fuzzy numbers. Similarity value of the STR is the intersection of two isosecle that been compared. To conclude that the query has a biological relationship with the male reference, the similarity of the YSTR locus is equal or more than 0.75 and the similarity value of the other 24 DNA profile loci is greater or equal to 0.5. From the trial that have been done, 90% give the right results.

Keywords


DNA profile; Fuzzy similarity; Loci DNA; Short tandem repeat; Y-chromosome

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DOI: https://doi.org/10.11591/eei.v13i1.5304

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Bulletin of EEI Stats

Bulletin of Electrical Engineering and Informatics (BEEI)
ISSN: 2089-3191, e-ISSN: 2302-9285
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